Vitamin K2 Mk-7

Vitamin K is necessary for normal blood clotting und synthesis of proteins found in plasma, bone, und kidneys.

Du schaust: Vitamin k2 mk-7

After some decades of studies today, we understand that vitamin K2 together MK-7 is essential for the function des several calcium-binding proteins involved an the maintenance von the normal structure von osteoarticular system, teeth, arterial wall, und for the regulation of cell growth.

Vitamin K is essential weil das the proper bildete and complete activation des the Gla proteins. Die Gla protein osteocalcin, wie man fully carboxylated über vitamin K, allows zum the binding of calcium to the bone matrix.


Natural vitamin K2 together MK-7 ist the vital cofactor weil das the enzyme γ-carboxylase which is able kommen sie carboxylate these calcium-regulating proteins making them maybe to form calcium-binding teams essential zum their organic activity. By controlling these proteins an vascular tissue, vitamin K2 keeps calcium out von the arteries und drive it zu bones.

Research has discovered that osteocalcin was undercarboxylated über 40% bei postmenopausal women wie man compared v premenopausal women (Knapen 1989). Uncarboxylated procession Gla-protein is damit verbundenen with ns increased vascular calcification und cardiovascular disease (Hackeng et al. 2001; Schurgers et al., 2013).

How do vitamins D3 und K2 arbeiten together?


The importance of vitamin D zum bone health has been recognised since it was used kommen sie eliminate rickets an the 1930s. Vitamin D ist a fat-soluble vitamin that functions as a hormone in the body kommen sie regulate calcium metabolism.

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Recent studies oase demonstrated that ns combination des vitamin K2 together MK-7 und Vitamin D3 ist more effective bei preventing bone loss than either nutrient alone. Taking just vitamin D may not be enough und very high doses once von year may have adverse effects.


With low levels of vitamin K2, there are a coincided lack von calcium an the bone and in increased concentration in the blood. This accumulation can lead kommen sie calcification in the ship wall des our arteries v clinical belang consequences, such together cardiovascular accidents und bone fractures.

This wake up because ns action des Vitamin K2 is impaired: vitamin K2 as MK-7 does notfall activate sufficient calcium-regulating vitamin-K2 dependent proteins, such as osteocalcin – making it able zu put calcium bei the skeletal – und the vascular protein MGP – i m sorry inhibits arterial calcification.

Additionally Vitamin D deshalb acts increasing die production of vitamin K2-dependent proteins, in order to raising ns body’s demand of vitamin K2.

The stamin connection between calcium und vitamin K2 has been described in the so-called calcium paradox where ns highest rates von hip fractures occur bei the countries with the highest calcium consumption.

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As defined von EFSA bei the “Scientific Opinion ~ above Dietary recommendation Values zum calcium” (May 2015), hypercalcaemia is unlikely to occur through high intake von calcium from the diet alone but kann sein be caused by high-dose calcium supplements, especially wie man accompanied by vitamin D supplements, together these kann increase calcium absorption.

organic Vitamin K2 as MK-7 und vitamin D must work bei combination kommen sie keep calcium bei the best places und having plenty von natural vitamin K2 together MK-7 bei the body permits us to profit from calcium und vitamin D like never before.
Other References:

Bolland et al., « Effect von calcium additionally on risk of myocardial infarction and cardiovascular events: meta-analysis » BMJ 2010

Kurnatowska et al., « The effect von vitamin k2 substitution on atherosclerosis und vascular calcification markers an non-dialysed patients an chronic kidney condition stage 3-5. » Nephrol. Dial. Transplant. 2013

Ushiroyama et al., « Effect von continuous an unified therapy through vitamin K2 und vitamin D3 on bone mineral density and coagulofibrinolysis function in postmenopausal women ». Maturitas 2002